Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20660950 | 1.00 | ABCB1 (0.47) | ABCB1FFAR2RIPK1GPR119KMT2A | |
| SCHEMBL22358312 | 1.00 | ABCB1 (0.47) | ABCB1FFAR2RIPK1GPR119KMT2A | |
| SCHEMBL20835764 | 1.00 | ABCB1 (0.47) | ABCB1FFAR2RIPK1GPR119KMT2A | |
| SCHEMBL20117225 | 1.00 | ABCB1 (0.47) | ABCB1FFAR2RIPK1GPR119KMT2A | |
| SCHEMBL12973332 | 0.90 | GPR119 (0.43) | ABCB1GPR119 | |
| SCHEMBL12973328 | 0.90 | NPC1 (0.41) | ABCB1GPR119KMT2A | |
| SCHEMBL24450861 | 0.89 | PDE4B (0.40) | ABCB1 | |
| SCHEMBL17877416 | 0.89 | PDE4B (0.40) | ABCB1 | |
| SCHEMBL22544464 | 0.89 | PDE4B (0.40) | ABCB1 | |
| SCHEMBL22544465 | 0.89 | PDE4B (0.40) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12275723-B2 | Compounds and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2025-04-15 | — | — | US | disclosed |
| US-20240400546-A1 | COMPOUNDS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2024-12-05 | — | — | US | disclosed |
| US-11970486-B2 | Compounds and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2024-04-30 | — | — | US | disclosed |
| US-20240124435-A1 | COMPOUNDS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2024-04-18 | — | — | US | disclosed |
| US-11873298-B2 | Compounds and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240124435-A1 | COMPOUNDS AND USES THEREOF | NLN, ACHE, CLN6 | ABCB1 129/4885FFAR2 4001/4885RIPK1 4414/4885 |
| US-11873298-B2 | Compounds and uses thereof | NLN, ACHE, CLN6 | ABCB1 129/4885FFAR2 4001/4885RIPK1 4414/4885 |
| US-20240400546-A1 | COMPOUNDS AND USES THEREOF | NLN, ACHE, CLN6 | ABCB1 129/4885FFAR2 4001/4885RIPK1 4414/4885 |
| US-12275723-B2 | Compounds and uses thereof | NLN, ACHE, CLN6 | ABCB1 129/4885FFAR2 4001/4885RIPK1 4414/4885 |
| US-11970486-B2 | Compounds and uses thereof | NLN, ACHE, CLN6 | ABCB1 129/4885FFAR2 4001/4885RIPK1 4414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.