Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 2/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | KMO | O15229 | 2/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | EIF2S1 | P05198 | 1/20 | 0.30 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30721173 | 0.87 | SCN5A (0.31) | KMOGLAHPGD | |
| SCHEMBL30721186 | 0.83 | NTRK1 (0.33) | METMAP4K4 | |
| SCHEMBL30721174 | 0.81 | MGLL (0.35) | KMO | |
| SCHEMBL30721176 | 0.73 | NTRK1 (0.33) | — | |
| SCHEMBL3258118 | 0.71 | PIK3CB (0.47) | JAK2MAP4K4GLAHPGD | |
| SCHEMBL921542 | 0.71 | KEAP1 (0.50) | MAP4K4EIF2AK3 | |
| SCHEMBL4874417 | 0.70 | PIK3C3 (0.39) | METCHRNA7MAP4K4 | |
| SCHEMBL31382799 | 0.70 | PIK3C3 (0.39) | METCHRNA7MAP4K4 | |
| SCHEMBL29966632 | 0.69 | MGLL (0.34) | — | |
| SCHEMBL9278316 | 0.67 | MEN1 (0.46) | KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260105-B | Aromatic heterocarbamic acid compound and preparation method and application thereof | 启东东岳药业有限公司 | 2024-01-16 | — | — | CN | disclosed |