Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.38 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.38 |
| ▸ | GGH | Q92820 | 1/20 | 0.35 |
| ▸ | EPOR | P19235 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.32 |
| ▸ | KDM4A | O75164 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.32 |
| ▸ | TET3 | O43151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3217804 | 0.86 | EPOR (0.44) | FOLH1GRM3NAALAD2GGHEPOR | |
| SCHEMBL3235961 | 0.82 | CPB2 (0.33) | — | |
| SCHEMBL2991471 | 0.75 | FOLH1 (0.50) | FOLH1GRM3NAALAD2GGHTET2 | |
| SCHEMBL10355086 | 0.75 | SLC6A2 (0.41) | FOLH1GRM3NAALAD2EPORTET2 | |
| SCHEMBL2991467 | 0.75 | FOLH1 (0.50) | FOLH1GRM3NAALAD2GGHTET2 | |
| SCHEMBL3186830 | 0.74 | ALOX15 (0.37) | EPOR | |
| SCHEMBL3195177 | 0.72 | EPOR (0.42) | FOLH1EPOR | |
| SCHEMBL3211443 | 0.71 | SMPD2 (0.33) | EPOR | |
| SCHEMBL3080982 | 0.71 | — | — | |
| SCHEMBL3217791 | 0.70 | SMPD2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | disclosed |
| US-7776844-B2 | N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use | YU RUEY J | 2010-08-17 | — | — | US | disclosed |
| US-20090208499-A1 | N-(Phosphonoalkyl)-Amino Acids, Derivatives Thereof and Compositions and Methods of Use | YU RUEY J | 2009-08-20 | — | — | US | disclosed |
| US-7572776-B2 | N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use | YU RUEY J | 2009-08-11 | — | — | US | disclosed |
| US-20080306025-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2008-12-11 | — | — | US | disclosed |
| US-7429575-B2 | N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use | YU RUEY J | 2008-09-30 | — | — | US | disclosed |
| US-20070161543-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2007-07-12 | — | — | US | disclosed |