Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27332954 | 1.00 | CTSS (0.47) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL30597634 | 1.00 | CTSS (0.47) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL18495625 | 1.00 | CTSS (0.47) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL30597646 | 1.00 | CTSS (0.47) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL25148113 | 0.98 | CTSS (0.48) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL31120787 | 0.94 | REN (0.50) | CTSBPTPN1 | |
| SCHEMBL31478692 | 0.91 | KLK5 (0.46) | CTSSCTSKCTSBCTSLMAPT | |
| SCHEMBL20646383 | 0.91 | KLK5 (0.46) | CTSSCTSKCTSBCTSLMAPT | |
| SCHEMBL17196273 | 0.91 | KLK5 (0.46) | CTSSCTSKCTSBCTSLMAPT | |
| SCHEMBL29539925 | 0.91 | KLK5 (0.46) | CTSSCTSKCTSBCTSLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4541796-A1 | EXATECAN DERIVATIVES AND USE THEREOF | Hangzhou Adcoris Biopharma Co., Ltd (CN) | 2025-04-23 | — | — | EP | disclosed |
| WO-2024022165-A1 | EXATECAN DERIVATIVES AND USE THEREOF | 杭州爱科瑞思生物医药有限公司 | 2024-02-01 | — | — | WO | disclosed |