SCHEMBL30722148

SCHEMBL30722148

CN1CCC(NC(=O)c2ccc3c(c2)sc2nc(-c4ccc(N5CCN(C(=O)OC(C)(C)C)CC5)cc4F)cn23)CC1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.53
▸ ALDH1A1 P00352 3/20 0.53
▸ KDM4E B2RXH2 2/20 0.53
▸ NPC1 O15118 1/20 0.53
▸ ATM Q13315 1/20 0.53
▸ HPGD P15428 2/20 0.51
▸ LMNA P02545 4/20 0.51
▸ TP53 P04637 4/20 0.51
▸ ALOX15 P16050 1/20 0.50
▸ HSD17B10 Q99714 1/20 0.50
▸ THRB P10828 2/20 0.49
▸ POLB P06746 1/20 0.47
▸ RXFP1 Q9HBX9 2/20 0.46
▸ BRD4 O60885 1/20 0.42
▸ FLT3 P36888 1/20 0.41
▸ SLC2A1 P11166 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26987383 1.00 MAPT (0.53) MAPTALDH1A1KDM4ENPC1ATM
SCHEMBL26987533 0.87 MAPT (0.51) MAPTALDH1A1KDM4ENPC1ATM
SCHEMBL30722123 0.87 MAPT (0.51) MAPTALDH1A1KDM4ENPC1ATM
SCHEMBL30722070 0.87 MAPT (0.51) MAPTALDH1A1KDM4ENPC1ATM
SCHEMBL26987706 0.87 MAPT (0.51) MAPTALDH1A1KDM4ENPC1ATM
SCHEMBL29924901 0.87 MAPT (0.59) MAPTALDH1A1KDM4ENPC1ATM
SCHEMBL30722115 0.86 MAPT (0.52) MAPTALDH1A1KDM4ENPC1ATM
SCHEMBL26987410 0.86 MAPT (0.52) MAPTALDH1A1KDM4ENPC1ATM
SCHEMBL30722249 0.86 MAPT (0.55) MAPTALDH1A1KDM4ENPC1ATM
SCHEMBL26987423 0.86 MAPT (0.55) MAPTALDH1A1KDM4ENPC1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4547672-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2025-05-07 — — EP disclosed
WO-2024010762-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2024-01-11 — — WO disclosed
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