Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29924958 | 0.89 | MAPT (0.69) | MAPTALDH1A1KDM4ENPC1ATM | |
| SCHEMBL24619425 | 0.88 | ABL1 (0.46) | MAPTALDH1A1KDM4ENPC1ATM | |
| SCHEMBL29924489 | 0.88 | ABL1 (0.46) | MAPTALDH1A1KDM4ENPC1ATM | |
| SCHEMBL30722148 | 0.87 | MAPT (0.53) | MAPTALDH1A1KDM4ENPC1ATM | |
| SCHEMBL26987383 | 0.87 | MAPT (0.53) | MAPTALDH1A1KDM4ENPC1ATM | |
| SCHEMBL30722122 | 0.87 | MAPT (0.46) | MAPTALDH1A1KDM4ENPC1ATM | |
| SCHEMBL26987414 | 0.87 | MAPT (0.46) | MAPTALDH1A1KDM4ENPC1ATM | |
| SCHEMBL31290657 | 0.87 | MAPT (0.46) | MAPTALDH1A1KDM4ENPC1ATM | |
| SCHEMBL30722088 | 0.87 | MAPT (0.52) | MAPTALDH1A1KDM4ENPC1ATM | |
| SCHEMBL30722090 | 0.87 | MAPT (0.52) | MAPTALDH1A1KDM4ENPC1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4274569-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | Anima Biotech Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022150316-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2022-07-14 | — | — | WO | disclosed |