Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KYNU | Q16719 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18594580 | 0.87 | SMN1; SMN2 (0.83) | SMN1; SMN2LMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL8389256 | 0.82 | SMN1; SMN2 (0.74) | SMN1; SMN2LMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL14288938 | 0.82 | LMNA (0.69) | SMN1; SMN2LMNAL3MBTL1CA1CA2 | |
| SCHEMBL3705526 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNAL3MBTL1CA1CA2 | |
| SCHEMBL7345362 | 0.79 | HDAC3 (0.57) | SMN1; SMN2LMNAL3MBTL1CA1CA2 | |
| SCHEMBL30823376 | 0.79 | SMN1; SMN2 (0.97) | SMN1; SMN2LMNAL3MBTL1CA1CA2 | |
| SCHEMBL18244515 | 0.78 | LMNA (0.52) | SMN1; SMN2LMNAL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL26127818 | 0.78 | LMNA (0.52) | SMN1; SMN2LMNAL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL26322851 | 0.78 | LMNA (0.52) | SMN1; SMN2LMNAL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL18244630 | 0.78 | LMNA (0.52) | SMN1; SMN2LMNAL3MBTL1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117615753-A | Lipid nanoparticle and method for preparing the same | 泰纳治疗公司 | 2024-02-27 | — | — | CN | disclosed |