Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24179526 | 1.00 | RXRA (0.31) | RXRARXRBRXRG | |
| SCHEMBL25917446 | 0.90 | RXRA (0.32) | RXRARXRBRXRG | |
| SCHEMBL30723993 | 0.89 | KDM4E (0.30) | — | |
| SCHEMBL25918022 | 0.89 | KDM4E (0.30) | — | |
| SCHEMBL25917448 | 0.84 | ALDH1A1 (0.32) | — | |
| SCHEMBL30724001 | 0.83 | RXRA (0.39) | RXRARXRBRXRG | |
| SCHEMBL25918142 | 0.83 | RXRA (0.39) | RXRARXRBRXRG | |
| SCHEMBL24179494 | 0.82 | RXRA (0.37) | RXRARXRBRXRG | |
| SCHEMBL30724048 | 0.76 | CYP4F2 (0.35) | RXRARXRBRXRG | |
| SCHEMBL25917544 | 0.76 | CYP4F2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006776-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND MEDICAL USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |