SCHEMBL3072391

SCHEMBL3072391

c1ccc2c(c1)nnn2-n1nnc2ccccc21

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 8/20 0.60
MAPT P10636 2/20 0.60
CYP2D6 P10635 2/20 0.60
POLB P06746 1/20 0.60
MAPK1 P28482 1/20 0.60
ATM Q13315 1/20 0.60
KEAP1 Q14145 1/20 0.60
ALDH1A1 P00352 1/20 0.60
CYP1A2 P05177 1/20 0.60
CYP3A4 P08684 1/20 0.60
CYP2C9 P11712 1/20 0.60
THPO P40225 1/20 0.60
CYP4Z1 Q86W10 1/20 0.60
DGAT1 O75907 1/20 0.59
GRM2 Q14416 1/20 0.50
RAB9A P51151 3/20 0.48
KCNMA1 Q12791 1/20 0.48
MGAM O43451 2/20 0.47
AMY1A P0DUB6 2/20 0.47
GAA P10253 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9464698 0.84 SLC9A1 (0.50) SLC9A1MAPTCYP2D6POLBMAPK1
SCHEMBL11272158 0.84 SLC9A1 (0.50) SLC9A1MAPTCYP2D6POLBMAPK1
SCHEMBL20710852 0.84 SLC9A1 (0.50) SLC9A1MAPTCYP2D6POLBMAPK1
SCHEMBL5635050 0.82 GAA (0.49) SLC9A1MAPTCYP2D6POLBMAPK1
SCHEMBL30518786 0.81 MAPK1 (0.49) SLC9A1MAPTCYP2D6POLBMAPK1
SCHEMBL13604183 0.81 SLC9A1 (0.52) SLC9A1MAPTCYP2D6POLBMAPK1
SCHEMBL2203699 0.80 MAPK1 (0.51) SLC9A1MAPTCYP2D6POLBMAPK1
SCHEMBL1021711 0.80 DGAT1 (0.46) SLC9A1MAPTCYP2D6POLBMAPK1
SCHEMBL9587958 0.78 DGAT1 (0.44) SLC9A1MAPTCYP2D6POLBMAPK1
SCHEMBL20059434 0.77 DGAT1 (0.43) SLC9A1MAPTCYP2D6POLBMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4291555-A1 SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES Celgene Corporation (US) 2023-12-20 EP disclosed
WO-2022173727-A1 SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES CELGENE CORPORATION (US) 2022-08-18 WO disclosed
CN-114149754-A Grid adhesive film and preparation method and application thereof 苏州赛伍应用技术股份有限公司 2022-03-08 CN disclosed
EP-2837419-A1 Honeycomb filter IBIDEN CO., LTD. (JP) 2015-02-18 EP disclosed
US-7833331-B2 Non-toxic corrosion-protection pigments based on cobalt UNIVERSITY OF DAYTON (US) 2010-11-16 US disclosed
US-7789958-B2 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON (US) 2010-09-07 US disclosed
US-20090163628-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON COBALT STURGILL JEFFREY ALLEN 2009-06-25 US disclosed
US-7537663-B2 Corrosion-inhibiting coating UNIVERSITY OF DAYTON (US) 2009-05-26 US disclosed
US-7422793-B2 Non-toxic corrosion-protection rinses and seals based on rare earth elements UNIVERSITY OF DAYTON (US) 2008-09-09 US disclosed
US-7407711-B2 Non-toxic corrosion-protection conversion coats based on rare earth elements UNIVERSITY OF DAYTON (US) 2008-08-05 US disclosed
EP-1472319-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2004-11-03 EP disclosed
WO-2004065305-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE UNIVERSITY OF DAYTON (US) 2004-08-05 WO disclosed
US-20040104377-A1 Non-toxic corrosion-protection pigments based on rare earth elements UNIVERSITY OF DAYTON 2004-06-03 US disclosed
US-20040020568-A1 Non-toxic corrosion-protection conversion coats based on rare earth elements DAYTON, UNIVERSITY OF 2004-02-05 US disclosed
US-20040016363-A1 CORROSION-INHIBITING COATING VENTURE LENDING & LEASING, IV, INC. 2004-01-29 US disclosed
US-20040016910-A1 Non-toxic corrosion-protection rinses and seals based on rare earth elements DAYTON, UNIVERSITY OF 2004-01-29 US disclosed
US-20040011252-A1 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON 2004-01-22 US disclosed
US-20030234063-A1 Non-toxic corrosion-protection conversion coats based on cobalt DAYTON, UNIVERSITY OF 2003-12-25 US disclosed
US-20030230363-A1 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON 2003-12-18 US disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed