Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.30 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30724013 | 0.92 | ESR1 (0.30) | — | |
| SCHEMBL30724000 | 0.87 | CCR1 (0.32) | EHMT2 | |
| SCHEMBL30723949 | 0.87 | EHMT2 (0.33) | EHMT2 | |
| SCHEMBL30724147 | 0.85 | RET (0.32) | — | |
| SCHEMBL30723812 | 0.84 | — | — | |
| SCHEMBL30724064 | 0.84 | DGAT2 (0.33) | — | |
| SCHEMBL30724062 | 0.84 | DGAT2 (0.33) | — | |
| SCHEMBL30723867 | 0.84 | NPC1 (0.33) | EHMT2 | |
| SCHEMBL30724076 | 0.84 | ESR1 (0.35) | — | |
| SCHEMBL30723863 | 0.84 | ATR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006776-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND MEDICAL USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |