Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.31 |
| ▸ | PDE9A | O76083 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24179437 | 0.83 | RXRA (0.38) | CYP4F2CYP4A11ALDH1A1LMNAPOLB | |
| SCHEMBL30724070 | 0.83 | RXRA (0.38) | CYP4F2CYP4A11ALDH1A1LMNAPOLB | |
| SCHEMBL24179522 | 0.72 | RET (0.31) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL24179481 | 0.72 | RXRA (0.38) | CYP4F2CYP4A11ALDH1A1LMNAPOLB | |
| SCHEMBL30723767 | 0.72 | RET (0.31) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL30724054 | 0.72 | CYP11B1 (0.34) | CYP11B1CYP11B2PDE9A | |
| SCHEMBL31178788 | 0.70 | CYP4F2 (0.44) | CYP4F2CYP4A11ALDH1A1LMNAPOLB | |
| SCHEMBL24004995 | 0.70 | CYP4F2 (0.44) | CYP4F2CYP4A11ALDH1A1LMNAPOLB | |
| SCHEMBL31128159 | 0.70 | CYP4F2 (0.44) | CYP4F2CYP4A11ALDH1A1LMNAPOLB | |
| SCHEMBL28673628 | 0.70 | CYP4F2 (0.49) | CYP4F2CYP4A11ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006776-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND MEDICAL USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |