Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | SOD1 | P00441 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 4/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30724137 | 0.93 | ALDH1A1 (0.52) | KMT2AMEN1CYP1A2MAPTALDH1A1 | |
| SCHEMBL30724119 | 0.93 | DRD4 (0.56) | KMT2AMEN1SOD1CYP1A2MAPT | |
| SCHEMBL30724150 | 0.90 | APP (0.58) | KMT2AMEN1CYP1A2MAPTALDH1A1 | |
| SCHEMBL11110472 | 0.90 | HPGD (0.56) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL30724143 | 0.87 | KMT2A (0.52) | KMT2AMEN1SOD1MAPTALDH1A1 | |
| SCHEMBL30724132 | 0.86 | ACHE (0.59) | KMT2ACYP1A2MAPTALDH1A1KDM4E | |
| SCHEMBL30724135 | 0.80 | NPC1 (0.57) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL11112195 | 0.80 | FLT3 (0.58) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL30724139 | 0.75 | NPC1 (0.54) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL5503814 | 0.74 | ALDH1A1 (0.65) | KMT2AMEN1CYP1A2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023234891-A2 | NOVEL ACETYLCHOLINESTERASE INHIBITORS | ISTANBUL MEDIPOL UNIVERSITESI (TR) | 2023-12-07 | — | — | WO | disclosed |