Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
| ▸ | CKS1B | P61024 | 2/20 | 0.33 |
| ▸ | SKP1 | P63208 | 2/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | CCNK | O75909 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CCND3 | P30281 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29174599 | 1.00 | STK17B (0.39) | STK17BSTK17AHSP90AA1HSP90AB1TTK | |
| SCHEMBL29174706 | 0.86 | HSP90AA1 (0.36) | STK17BSTK17AHSP90AA1HSP90AB1TTK | |
| SCHEMBL30725531 | 0.86 | HSP90AA1 (0.36) | STK17BSTK17AHSP90AA1HSP90AB1TTK | |
| SCHEMBL25329417 | 0.77 | STK17B (0.42) | STK17BSTK17AHSP90AA1HSP90AB1TTK | |
| SCHEMBL30725475 | 0.77 | STK17B (0.42) | STK17BSTK17AHSP90AA1HSP90AB1TTK | |
| SCHEMBL30493899 | 0.76 | SYK (0.40) | STK17BSTK17ATTKBTKSCN9A | |
| SCHEMBL14771769 | 0.75 | STK17B (0.35) | STK17BSTK17AHSP90AA1HSP90AB1POLB | |
| SCHEMBL30725494 | 0.72 | MAP2K4 (0.41) | STK17BSTK17AHSP90AA1HSP90AB1TTK | |
| SCHEMBL16653684 | 0.72 | MAP2K4 (0.41) | STK17BSTK17AHSP90AA1HSP90AB1TTK | |
| SCHEMBL30919548 | 0.70 | PDK4 (0.39) | STK17BSTK17ACKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430589-A | 2-aminopyrimidine compound or salt thereof, and preparation method and application thereof | 励缔(杭州)医药科技有限公司 | 2024-01-23 | — | — | CN | disclosed |