Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 4/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | STK17B | O94768 | 1/20 | 0.36 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 2/20 | 0.35 |
| ▸ | SKP1 | P63208 | 2/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | CCNK | O75909 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16653684 | 1.00 | MAP2K4 (0.41) | MAP2K4RORCRARGSTK17BSTK17A | |
| SCHEMBL22911971 | 0.80 | PIM1 (0.50) | STK17BSTK17ARPS6KA5L3MBTL1HSP90AA1 | |
| SCHEMBL29595692 | 0.80 | PIM1 (0.50) | STK17BSTK17ARPS6KA5L3MBTL1HSP90AA1 | |
| SCHEMBL7016168 | 0.77 | L3MBTL1 (0.44) | MAP2K4CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL19100171 | 0.74 | RPS6KA5 (0.41) | RPS6KA5KDM4ECDK9 | |
| SCHEMBL19100608 | 0.74 | MAP2K4 (0.43) | MAP2K4RORCCHRM2CHRM4CHRM1 | |
| SCHEMBL29057628 | 0.74 | MAP2K4 (0.50) | MAP2K4RORCKDM4EALDH1A1CYP11B2 | |
| SCHEMBL8216089 | 0.73 | ELANE (0.52) | MAP2K4CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL30725430 | 0.72 | STK17B (0.39) | STK17BSTK17ARPS6KA5CKS1BSKP1 | |
| SCHEMBL29174599 | 0.72 | STK17B (0.39) | STK17BSTK17ARPS6KA5CKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430589-A | 2-aminopyrimidine compound or salt thereof, and preparation method and application thereof | 励缔(杭州)医药科技有限公司 | 2024-01-23 | — | — | CN | disclosed |