SCHEMBL30725574

SCHEMBL30725574

[O-][n+]1ccc(Cl)cc1CCl

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 1/20 0.32
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
AHR P35869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11258812 0.76 RAB9A (0.33) CYP3A4ALOX15SMN1; SMN2TDP1
SCHEMBL4456284 0.73 AHR (0.39) HDAC8AHR
SCHEMBL4928856 0.73
SCHEMBL29620985 0.73
SCHEMBL8897244 0.71 HTR3E (0.32)
SCHEMBL6136498 0.70
SCHEMBL21355649 0.70
SCHEMBL6136567 0.70
SCHEMBL7641629 0.70
SCHEMBL31312464 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111511728-B Compound for separating rare earth elements and s, p, d metals, separation method and use thereof 有机生物化学公司 2023-12-08 CN disclosed