Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | GFER | P55789 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6298255 | 0.84 | MEN1 (0.48) | MAPTRAB9ANPC1CYP1A2CYP2C9 | |
| SCHEMBL476742 | 0.81 | MEN1 (0.51) | MAPTRAB9AHPGDNPC1GFER | |
| SCHEMBL31039595 | 0.81 | MEN1 (0.51) | MAPTRAB9AHPGDNPC1GFER | |
| SCHEMBL9926877 | 0.81 | RAB9A (0.51) | MAPTRAB9AHPGDNPC1GFER | |
| SCHEMBL5382099 | 0.80 | RAB9A (0.50) | MAPTRAB9AHPGDNPC1GFER | |
| SCHEMBL24543271 | 0.79 | MAPT (0.55) | MAPTRAB9AHPGDNPC1GFER | |
| SCHEMBL29368311 | 0.79 | MAPT (0.55) | MAPTRAB9AHPGDNPC1GFER | |
| SCHEMBL30032844 | 0.77 | HPGD (0.54) | RAB9AHPGDNPC1KMT2AFGFR1 | |
| SCHEMBL18289116 | 0.74 | CYP11B2 (0.47) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL2627244 | 0.74 | IRAK4 (0.53) | MAPTRAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117186066-A | Indazole ALK5 inhibitor and preparation method and application thereof | 中国药科大学 | 2023-12-08 | — | — | CN | disclosed |