Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 3/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 3/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29172508 | 1.00 | L3MBTL1 (0.41) | L3MBTL1PDE4APDE4DALDH1A1PDE4B | |
| SCHEMBL30725861 | 0.88 | CFTR (0.44) | L3MBTL1PDE4APDE4DALDH1A1PDE4B | |
| SCHEMBL5518753 | 0.85 | L3MBTL1 (0.58) | L3MBTL1MEN1KMT2ASMN1; SMN2CNR1 | |
| SCHEMBL3515098 | 0.84 | MAPT (0.42) | L3MBTL1ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL29172516 | 0.81 | L3MBTL1 (0.48) | L3MBTL1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL30725860 | 0.81 | L3MBTL1 (0.48) | L3MBTL1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL16014237 | 0.81 | L3MBTL1 (0.41) | L3MBTL1PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL3515950 | 0.81 | L3MBTL1 (0.47) | L3MBTL1PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL29172523 | 0.80 | MAPT (0.42) | L3MBTL1ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL16014236 | 0.79 | DGAT1 (0.34) | NPC1CNR1ACHECNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117186066-A | Indazole ALK5 inhibitor and preparation method and application thereof | 中国药科大学 | 2023-12-08 | — | — | CN | disclosed |