Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29172482 | 1.00 | L3MBTL1 (0.44) | L3MBTL1KMT2ANPC1RAB9AABCB1 | |
| SCHEMBL29172522 | 0.94 | L3MBTL1 (0.43) | L3MBTL1KMT2ANPC1RAB9AABCB1 | |
| SCHEMBL30725860 | 0.91 | L3MBTL1 (0.48) | L3MBTL1KMT2ANPC1RAB9AABCB1 | |
| SCHEMBL29172516 | 0.91 | L3MBTL1 (0.48) | L3MBTL1KMT2ANPC1RAB9AABCB1 | |
| SCHEMBL30725850 | 0.90 | L3MBTL1 (0.46) | L3MBTL1KMT2ANPC1RAB9AABCB1 | |
| SCHEMBL29172513 | 0.90 | L3MBTL1 (0.46) | L3MBTL1KMT2ANPC1RAB9AABCB1 | |
| SCHEMBL29172523 | 0.87 | MAPT (0.42) | L3MBTL1KMT2ANPC1RAB9AABCB1 | |
| SCHEMBL30725845 | 0.86 | BRAF (0.48) | MAPT | |
| SCHEMBL29172518 | 0.86 | BRAF (0.48) | MAPT | |
| SCHEMBL29172520 | 0.79 | CYP11B1 (0.46) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117186066-A | Indazole ALK5 inhibitor and preparation method and application thereof | 中国药科大学 | 2023-12-08 | — | — | CN | disclosed |