Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | TEK | Q02763 | 5/20 | 0.47 |
| ▸ | GRM5 | P41594 | 6/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29172518 | 1.00 | BRAF (0.48) | BRAFTEKGRM5LRRK2ATR | |
| SCHEMBL29172520 | 0.93 | CYP11B1 (0.46) | BRAFTEKLRRK2MAPTABL1 | |
| SCHEMBL30725852 | 0.93 | CYP11B1 (0.46) | BRAFTEKLRRK2MAPTABL1 | |
| SCHEMBL29172524 | 0.90 | PRKCA (0.43) | MAPTABL1PDGFRBBCRPDGFRA | |
| SCHEMBL30725867 | 0.89 | BRAF (0.45) | BRAFTEKKDM4EMAPTABL1 | |
| SCHEMBL29172485 | 0.89 | BRAF (0.45) | BRAFTEKKDM4EMAPTABL1 | |
| SCHEMBL29172517 | 0.86 | CYP11B1 (0.47) | KDM4EMAPTABL1PDGFRBBCR | |
| SCHEMBL30725853 | 0.86 | CYP11B1 (0.47) | KDM4EMAPTABL1PDGFRBBCR | |
| SCHEMBL30725868 | 0.86 | L3MBTL1 (0.44) | MAPT | |
| SCHEMBL29172482 | 0.86 | L3MBTL1 (0.44) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117186066-A | Indazole ALK5 inhibitor and preparation method and application thereof | 中国药科大学 | 2023-12-08 | — | — | CN | disclosed |