Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
| ▸ | WNK1 | Q9H4A3 | 2/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | BCL6 | P41182 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15174387 | 1.00 | MEN1 (0.49) | MEN1KMT2AMAPTMAPK1HCAR3 | |
| SCHEMBL15740508 | 0.94 | MEN1 (0.57) | MEN1KMT2AMAPTMAPK1HCAR3 | |
| SCHEMBL15740481 | 0.94 | MEN1 (0.53) | MEN1KMT2AMAPTMAPK1HCAR3 | |
| SCHEMBL10270108 | 0.93 | MEN1 (0.44) | MEN1KMT2AMAPTMAPK1HCAR3 | |
| SCHEMBL15740701 | 0.93 | KMT2A (0.59) | MEN1KMT2AMAPTMAPK1HCAR3 | |
| SCHEMBL26774910 | 0.92 | BCL6 (0.47) | MEN1KMT2AMAPTMAPK1HCAR3 | |
| SCHEMBL572975 | 0.90 | HCAR3 (0.48) | MEN1KMT2AMAPTMAPK1HCAR3 | |
| SCHEMBL572153 | 0.90 | HCAR3 (0.48) | MEN1KMT2AMAPTMAPK1HCAR3 | |
| SCHEMBL572154 | 0.90 | HCAR3 (0.48) | MEN1KMT2AMAPTMAPK1HCAR3 | |
| SCHEMBL30578514 | 0.90 | MEN1 (0.41) | MEN1KMT2AMAPTMAPK1HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558495-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | Bristol-Myers Squibb Company (US) | 2025-05-28 | — | — | EP | disclosed |
| WO-2024020084-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-01-25 | — | — | WO | disclosed |