SCHEMBL30906440

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)O)C(C)C

nearest known ligand 0.68

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	KEAP1	Q14145	1/20	0.68

▸	PTH1R	Q03431	8/20	0.62

▸	MAPK8	P45983	1/20	0.60

▸	MAPK9	P45984	1/20	0.60

▸	MAPK10	P53779	1/20	0.60

▸	KDM1A	O60341	2/20	0.60

▸	GLP1R	P43220	3/20	0.58

▸	VIPR1	P32241	3/20	0.58

▸	VIPR2	P41587	2/20	0.58

▸	TFPI	P10646	1/20	0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30906548	0.94	KEAP1 (0.72)	KEAP1PTH1RMAPK8MAPK9MAPK10
SCHEMBL30906447	0.94	KEAP1 (0.66)	KEAP1PTH1RMAPK8MAPK9MAPK10
SCHEMBL30495695	0.94	KEAP1 (0.61)	KEAP1PTH1RGLP1R
SCHEMBL30432166	0.93	KEAP1 (0.65)	KEAP1PTH1RMAPK8MAPK9MAPK10
SCHEMBL30906363	0.93	KEAP1 (0.65)	KEAP1PTH1RMAPK8MAPK9MAPK10
SCHEMBL30726561	0.92	KEAP1 (0.68)	KEAP1PTH1RMAPK8MAPK9MAPK10
SCHEMBL31000892	0.92	KEAP1 (0.61)	KEAP1PTH1RMAPK8MAPK9MAPK10
SCHEMBL30824283	0.91	KEAP1 (0.71)	KEAP1PTH1RMAPK8MAPK9MAPK10
SCHEMBL30906522	0.91	MAPK8 (0.67)	KEAP1PTH1RMAPK8MAPK9MAPK10
SCHEMBL30906421	0.91	KEAP1 (0.68)	KEAP1PTH1RMAPK8MAPK9MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4598964-A2	ANTI-IGE ANTIBODIES	Abwiz Bio, Inc. (US)	2025-08-13	—	—	EP	disclosed
US-20240182599-A1	ANTI-IGE ANTIBODIES	ABWIZ BIO, INC.	2024-06-06	—	—	US	disclosed
WO-2024076785-A2	ANTI-IGE ANTIBODIES	ABWIZ BIO, INC. (US)	2024-04-11	—	—	WO	disclosed