SCHEMBL30726587

CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)O)C(C)C)[C@@H](C)O)C(C)C)C(C)C

nearest known ligand 0.61

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	RAMP3	O60896	3/20	0.61

▸	CALCR	P30988	3/20	0.61

▸	OPRM1	P35372	2/20	0.57

▸	OPRD1	P41143	2/20	0.57

▸	NTSR1	P30989	2/20	0.57

▸	NMUR2	Q9GZQ4	3/20	0.56

▸	NMUR1	Q9HB89	3/20	0.56

▸	F2	P00734	3/20	0.54

▸	NPY2R	P49146	5/20	0.54

▸	NPY4R	P50391	5/20	0.54

▸	NPY5R	Q15761	5/20	0.54

▸	NPY1R	P25929	3/20	0.54

▸	EP300	Q09472	1/20	0.54

▸	HIF1A	Q16665	1/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31000918	0.96	RAMP3 (0.58)	RAMP3CALCROPRM1OPRD1NTSR1
SCHEMBL29856042	0.93	RAMP3 (0.56)	RAMP3CALCROPRM1OPRD1NTSR1
SCHEMBL30906513	0.93	RAMP3 (0.55)	RAMP3CALCROPRM1OPRD1NTSR1
SCHEMBL30906353	0.89	CALCR (0.59)	CALCRNTSR1F2NPY2RNPY4R
SCHEMBL30495700	0.88	OPRM1 (0.60)	RAMP3CALCROPRM1OPRD1NTSR1
SCHEMBL31182741	0.88	CALCR (0.62)	RAMP3CALCRNMUR2NMUR1F2
SCHEMBL38665584	0.87	CALCRL (0.60)	NTSR1EP300HIF1A
SCHEMBL29376302	0.87	OPRM1 (0.64)	RAMP3CALCROPRM1OPRD1NTSR1
SCHEMBL30625026	0.87	OPRM1 (0.64)	RAMP3CALCROPRM1OPRD1NTSR1
SCHEMBL30428845	0.87	OPRM1 (0.63)	RAMP3CALCROPRM1OPRD1NMUR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024020063-A2	ANTI-HRF ANTIBODIES	LA JOLLA INSTITUTE FOR IMMUNOLOGY (US)	2024-01-25	—	—	WO	disclosed