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SCHEMBL29376302

SCHEMBL29376302

CC(C)C[C@H](N)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)O)[C@@H](C)O

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 5/20 0.64
▸ OPRD1 P41143 5/20 0.64
▸ RAMP3 O60896 1/20 0.57
▸ CALCR P30988 1/20 0.57
▸ NMUR2 Q9GZQ4 3/20 0.56
▸ NMUR1 Q9HB89 3/20 0.56
▸ SLC6A2 P23975 1/20 0.56
▸ NTSR1 P30989 2/20 0.55
▸ F2 P00734 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30625026 1.00 OPRM1 (0.64) OPRM1OPRD1RAMP3CALCRNMUR2
SCHEMBL29884130 0.92 OPRM1 (0.61) OPRM1OPRD1RAMP3CALCRNMUR2
SCHEMBL29581123 0.90 OPRM1 (0.56) OPRM1OPRD1RAMP3CALCRNMUR2
SCHEMBL31130613 0.90 CALCR (0.56) OPRM1OPRD1RAMP3CALCRNMUR2
SCHEMBL30906513 0.88 RAMP3 (0.55) OPRM1OPRD1RAMP3CALCRNMUR2
SCHEMBL29993441 0.87 OPRM1 (0.59) OPRM1OPRD1
SCHEMBL29856042 0.87 RAMP3 (0.56) OPRM1OPRD1RAMP3CALCRNMUR2
SCHEMBL30726587 0.87 RAMP3 (0.61) OPRM1OPRD1RAMP3CALCRNMUR2
SCHEMBL31020744 0.87 SLC6A2 (0.63) OPRM1OPRD1NMUR2NMUR1SLC6A2
SCHEMBL31000918 0.87 RAMP3 (0.58) OPRM1OPRD1RAMP3CALCRNMUR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12227563-B2 Anti-IGF-I receptor humanized antibody TEIJIN PHARMA LIMITED (JP) 2025-02-18 — — US disclosed
CN-113286612-B Humanized antibodies against IGF-I receptor 帝人制药株式会社 2024-12-24 — — CN disclosed
US-20230192868-A1 ANTI-IGF-I RECEPTOR ANTIBODY TEIJIN PHARMA LIMITED (JP) 2023-06-22 — — US disclosed
US-11629194-B2 Anti-IGF-I receptor antibodies, encoding nucleic acid molecules and methods of using said antibodies TEIJIN PHARMA LIMITED (JP) 2023-04-18 — — US disclosed
US-20220033485-A1 ANTI-IGF-I RECEPTOR HUMANIZED ANTIBODY TEIJIN PHARMA LIMITED (JP) 2022-02-03 — — US disclosed
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