SCHEMBL3072667

SCHEMBL3072667

O/N=C/c1c(O)ccc2ccccc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.67
KMT2A Q03164 7/20 0.67
KDM4E B2RXH2 8/20 0.65
MEN1 O00255 6/20 0.65
L3MBTL1 Q9Y468 5/20 0.65
ALDH1A1 P00352 4/20 0.65
GAA P10253 3/20 0.65
HPGD P15428 3/20 0.65
RRM1 P23921 2/20 0.65
ATM Q13315 1/20 0.65
THRB P10828 3/20 0.63
POLB P06746 2/20 0.63
MPI P34949 2/20 0.63
ALOX15 P16050 1/20 0.63
TSHR P16473 1/20 0.63
HSD17B10 Q99714 1/20 0.63
CRHBP P24387 1/20 0.63
CRHR2 Q13324 1/20 0.63
BLM P54132 1/20 0.63
CASP6 P55212 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3072670 1.00 MAPT (0.67) MAPTKMT2AKDM4EMEN1L3MBTL1
SCHEMBL29361295 0.86 RRM1 (0.83) MAPTKMT2AKDM4EMEN1L3MBTL1
SCHEMBL12760863 0.86 RRM1 (0.83) MAPTKMT2AKDM4EMEN1L3MBTL1
SCHEMBL7598549 0.86 RRM1 (0.83) MAPTKMT2AKDM4EMEN1L3MBTL1
SCHEMBL30712963 0.85 MAPT (0.67) MAPTKMT2AKDM4EMEN1L3MBTL1
SCHEMBL2314986 0.85 MAPT (0.67) MAPTKMT2AKDM4EMEN1L3MBTL1
SCHEMBL2314206 0.85 MAPT (0.67) MAPTKMT2AKDM4EMEN1L3MBTL1
SCHEMBL17067845 0.83 MAPT (0.68) MAPTKMT2AKDM4EMEN1L3MBTL1
SCHEMBL10783543 0.83 MAPT (0.65) MAPTKMT2AKDM4EMEN1L3MBTL1
SCHEMBL10783539 0.83 MAPT (0.65) MAPTKMT2AKDM4EMEN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114262282-B Aldoxime compound and preparation method and application thereof 广东省科学院资源利用与稀土开发研究所 2024-04-19 CN disclosed
US-20220304958-A1 SMALL MOLECULE INHIBITORS OF A PROTEIN COMPLEX THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-09-29 US disclosed
CN-114262282-A Aldoxime compound and preparation method and application thereof 广东省科学院资源利用与稀土开发研究所 2022-04-01 CN disclosed
WO-2020247608-A1 SMALL MOLECULE INHIBITORS OF A PROTEIN COMPLEX THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-12-10 WO disclosed
US-10696932-B2 Cleaning composition FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2020-06-30 US disclosed
US-10345707-B2 Stripping process FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2019-07-09 US disclosed
US-20190016999-A1 CLEANING COMPOSITION FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2019-01-17 US disclosed
US-20180136563-A1 Stripping Process FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2018-05-17 US disclosed
US-20180136563-A1 Stripping Process FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2018-05-17 US disclosed
US-20170255100-A1 DRY FILM STRUCTURE FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2017-09-07 US disclosed
US-20040016910-A1 Non-toxic corrosion-protection rinses and seals based on rare earth elements DAYTON, UNIVERSITY OF 2004-01-29 US disclosed
US-20040011252-A1 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON 2004-01-22 US disclosed
US-20030234063-A1 Non-toxic corrosion-protection conversion coats based on cobalt DAYTON, UNIVERSITY OF 2003-12-25 US disclosed
US-20030230363-A1 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON 2003-12-18 US disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
EP-0584988-B1 Process for the preparation of salicylaldoxine derivatives ZENECA LTD (GB) 1996-10-23 EP disclosed
US-5502254-A Method for the preparation of 2-hydroxyarylaldoximes ZENECA LIMITED (GB) 1996-03-26 US disclosed
EP-0584988-A1 Process for the preparation of salicylaldoxine derivatives ZENECA LIMITED (GB) 1994-03-02 EP disclosed
US-5100532-A In liquid hydrocarbonaceous media BETZ LABORATORIES, INC. (US) 1992-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220304958-A1 SMALL MOLECULE INHIBITORS OF A PROTEIN COMPLEX SERBP1, PPHLN1, VCAM1 MAPT 2384/4885KMT2A 1161/4885KDM4E 1046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.