Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.33 |
| ▸ | USP19 | O94966 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26983572 | 1.00 | CYP1A2 (0.39) | CYP1A2CYP2C19CYP2C9ACHEALDH1A1 | |
| SCHEMBL31023116 | 0.74 | CYP1A2 (0.49) | CYP1A2CYP2C19CYP2C9ACHEALDH1A1 | |
| SCHEMBL21598055 | 0.73 | CYP1A2 (0.51) | CYP1A2CYP2C19CYP2C9ACHEALDH1A1 | |
| SCHEMBL17789326 | 0.69 | ALDH1A1 (0.47) | CYP1A2CYP2C19CYP2C9ACHEALDH1A1 | |
| SCHEMBL24453964 | 0.68 | CYP2C9 (0.40) | CYP1A2CYP2C19CYP2C9ACHEALDH1A1 | |
| SCHEMBL29534121 | 0.68 | CYP2C9 (0.40) | CYP1A2CYP2C19CYP2C9ACHEALDH1A1 | |
| SCHEMBL1274042 | 0.68 | ALDH1A1 (0.44) | CYP1A2CYP2C19CYP2C9ALDH1A1RPS6KA3 | |
| SCHEMBL633043 | 0.68 | TSHR (0.43) | CYP1A2CYP2C19CYP2C9ALDH1A1LMNA | |
| SCHEMBL26983627 | 0.67 | KDM4E (0.34) | ALDH1A1 | |
| SCHEMBL26983543 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739680-A1 | SOLID FORMS OF TRPV4 ANTAGONISTS | Actio Biosciences, Inc. (US) | 2026-05-13 | — | — | EP | disclosed |
| EP-4551572-A1 | THERAPEUTIC COMPOUNDS AND METHODS | Actio Biosciences, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| CN-119790051-A | Therapeutic compounds and methods | 爱克堤欧生物科学股份有限公司 | 2025-04-08 | — | — | CN | disclosed |
| WO-2025014818-A1 | SOLID FORMS OF GSK2798745, A TRPV4 ANTAGONIST | ACTIO BIOSCIENCES, INC. (US) | 2025-01-16 | — | — | WO | disclosed |
| WO-2024011214-A1 | THERAPEUTIC COMPOUNDS AND METHODS | ACTIO BIOSCIENCES, INC. (US) | 2024-01-11 | — | — | WO | disclosed |