Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21598055 | 0.92 | CYP1A2 (0.51) | CYP1A2CYP2C9CYP2C19ACHEALDH1A1 | |
| SCHEMBL5837627 | 0.77 | CYP1A2 (0.43) | CYP1A2CYP2C9CYP2C19ACHEALDH1A1 | |
| Hydrochloric Acid SCHEMBL5837668 | 0.76 | CYP1A2 (0.42) | CYP1A2CYP2C9CYP2C19ACHEALDH1A1 | |
| SCHEMBL1581709 | 0.75 | CYP1B1 (0.59) | CYP1A2CYP2C9CYP2C19ACHEALDH1A1 | |
| SCHEMBL633043 | 0.75 | TSHR (0.43) | CYP1A2CYP2C9CYP2C19ALDH1A1GAA | |
| SCHEMBL30726985 | 0.74 | CYP1A2 (0.39) | CYP1A2CYP2C9CYP2C19ACHEALDH1A1 | |
| SCHEMBL26983572 | 0.74 | CYP1A2 (0.39) | CYP1A2CYP2C9CYP2C19ACHEALDH1A1 | |
| SCHEMBL14218828 | 0.73 | ALDH1A1 (0.41) | CYP1A2CYP2C9CYP2C19ACHEALDH1A1 | |
| SCHEMBL24453964 | 0.72 | CYP2C9 (0.40) | CYP1A2CYP2C9CYP2C19ACHEALDH1A1 | |
| SCHEMBL29534121 | 0.72 | CYP2C9 (0.40) | CYP1A2CYP2C9CYP2C19ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A9 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-08-02 | — | — | WO | disclosed |