Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27165059 | 1.00 | LMNA (0.37) | LMNARORCNPSR1ALDH1A1C5AR1 | |
| SCHEMBL26983676 | 0.85 | LMNA (0.37) | LMNARORCNPSR1ALDH1A1C5AR1 | |
| SCHEMBL30726987 | 0.85 | LMNA (0.37) | LMNARORCNPSR1ALDH1A1C5AR1 | |
| SCHEMBL30727014 | 0.75 | LMNA (0.34) | LMNARORCNPSR1ALDH1A1C5AR1 | |
| SCHEMBL26990598 | 0.75 | LMNA (0.34) | LMNARORCNPSR1ALDH1A1C5AR1 | |
| SCHEMBL9981990 | 0.70 | METAP2 (0.30) | — | |
| SCHEMBL10257396 | 0.70 | CYP1A2 (0.39) | NPSR1ALDH1A1ICMTTSHRTDP1 | |
| SCHEMBL30727008 | 0.68 | C5AR1 (0.36) | LMNANPSR1ALDH1A1C5AR1HTT | |
| SCHEMBL26983576 | 0.68 | C5AR1 (0.36) | LMNANPSR1ALDH1A1C5AR1HTT | |
| SCHEMBL14498503 | 0.67 | POLB (0.30) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739680-A1 | SOLID FORMS OF TRPV4 ANTAGONISTS | Actio Biosciences, Inc. (US) | 2026-05-13 | — | — | EP | disclosed |
| EP-4551572-A1 | THERAPEUTIC COMPOUNDS AND METHODS | Actio Biosciences, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| CN-119790051-A | Therapeutic compounds and methods | 爱克堤欧生物科学股份有限公司 | 2025-04-08 | — | — | CN | disclosed |
| WO-2025014818-A1 | SOLID FORMS OF GSK2798745, A TRPV4 ANTAGONIST | ACTIO BIOSCIENCES, INC. (US) | 2025-01-16 | — | — | WO | disclosed |
| WO-2024011214-A1 | THERAPEUTIC COMPOUNDS AND METHODS | ACTIO BIOSCIENCES, INC. (US) | 2024-01-11 | — | — | WO | disclosed |