Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24662921 | 0.83 | SMN1; SMN2 (0.39) | SMN1; SMN2NPC1RAB9AMAPTLMNA | |
| SCHEMBL15068628 | 0.81 | ALDH1A1 (0.31) | SMN1; SMN2NPC1RAB9AMAPTKMT2A | |
| SCHEMBL25359012 | 0.75 | PDE4B (0.32) | SMN1; SMN2MAPTKMT2AALDH1A1MAPK1 | |
| SCHEMBL28529693 | 0.73 | SMN1; SMN2 (0.44) | SMN1; SMN2KMT2AALDH1A1MAPK1 | |
| SCHEMBL16376282 | 0.73 | SMN1; SMN2 (0.37) | SMN1; SMN2MAPTKMT2ALMNAL3MBTL1 | |
| SCHEMBL25456973 | 0.71 | AHR (0.31) | — | |
| SCHEMBL24163472 | 0.70 | ALDH1A1 (0.41) | SMN1; SMN2NPC1RAB9AMAPTKMT2A | |
| SCHEMBL31400377 | 0.70 | — | — | |
| SCHEMBL23756860 | 0.68 | — | — | |
| SCHEMBL31732100 | 0.67 | HTT (0.33) | SMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532495-A1 | CD73 INHIBITOR COMPOUNDS | Adorx therapeutics Limited (GB) | 2025-04-09 | — | — | EP | disclosed |
| CN-119585273-A | CD73 inhibitor compounds | 阿道尔克斯治疗有限公司 | 2025-03-07 | — | — | CN | disclosed |
| WO-2023233130-A1 | CD73 INHIBITOR COMPOUNDS | AdoRx Therapeutics Limited (GB) | 2023-12-07 | — | — | WO | disclosed |