Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.44 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.38 |
| ▸ | HTR3B | O95264 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.38 |
| ▸ | KCNK13 | Q9HB14 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31137271 | 0.79 | LCK (0.54) | RPS6KA5LCK | |
| SCHEMBL969006 | 0.75 | PDE10A (0.50) | RPS6KA5PDE10ALCK | |
| SCHEMBL31136356 | 0.74 | ACSS2 (0.35) | PDE10A | |
| Hydrochloric Acid SCHEMBL31136484 | 0.73 | ACSS2 (0.34) | PDE10A | |
| SCHEMBL31136800 | 0.72 | LCK (0.38) | PDE10ALCK | |
| SCHEMBL30899540 | 0.72 | LCK (0.44) | RPS6KA5RAD51HTR3EHTR3BHTR3A | |
| SCHEMBL31253280 | 0.71 | ILK (0.42) | PDE10A | |
| SCHEMBL10846882 | 0.71 | HCRTR1 (0.46) | RAD51 | |
| SCHEMBL31040891 | 0.70 | TDP1 (0.46) | — | |
| SCHEMBL30755153 | 0.70 | RPS6KA5 (0.42) | RPS6KA5RAD51KCNK13LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024002376-A1 | PRMT5 INHIBITORS AND USE THEREOF | 上海赛岚生物科技有限公司 | 2024-01-04 | — | — | WO | disclosed |