Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | JAK1 | P23458 | 1/20 | 0.56 |
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29913505 | 1.00 | JAK2 (0.56) | JAK2JAK1GPR119MEN1KMT2A | |
| SCHEMBL803527 | 0.84 | JAK2 (0.74) | JAK2JAK1GPR119MEN1KMT2A | |
| SCHEMBL12736035 | 0.84 | GPR119 (0.58) | JAK2JAK1GPR119MEN1KMT2A | |
| SCHEMBL29913629 | 0.82 | GPR119 (0.59) | JAK2JAK1GPR119 | |
| SCHEMBL5571027 | 0.81 | FAAH (0.56) | GPR119MEN1KMT2AKDM4E | |
| SCHEMBL25389253 | 0.78 | GPR119 (0.59) | JAK2JAK1GPR119MEN1KMT2A | |
| SCHEMBL8111282 | 0.78 | JAK2 (0.78) | JAK2JAK1GPR119MEN1KMT2A | |
| SCHEMBL8111279 | 0.78 | JAK2 (0.78) | JAK2JAK1GPR119MEN1KMT2A | |
| SCHEMBL14285890 | 0.78 | GPR119 (0.63) | GPR119 | |
| SCHEMBL621706 | 0.77 | GPR119 (0.51) | JAK2JAK1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117480161-A | Novel 2, 3-dihydro-1H-pyrrolo [3,2-b ] pyridine derivatives as sigma ligands | 塔拉森调理公司 | 2024-01-30 | — | — | CN | disclosed |