SCHEMBL30728210

SCHEMBL30728210

CCC(O)c1cccc(C(F)(F)F)c1

nearest known ligand 0.70

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.70
PDE2A O00408 1/20 0.54
LMNA P02545 1/20 0.52
CES2 O00748 1/20 0.51
MEN1 O00255 1/20 0.49
ALDH1A1 P00352 1/20 0.49
CYP1A2 P05177 1/20 0.49
POLB P06746 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
KMT2A Q03164 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
GRIN2B Q13224 2/20 0.48
ACP3 P15309 2/20 0.47
IDO1 P14902 1/20 0.45
TDO2 P48775 1/20 0.45
HTR2A P28223 1/20 0.45
HTR2C P28335 1/20 0.45
HTR2B P41595 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4669029 1.00 PNMT (0.70) PNMTPDE2ALMNACES2MEN1
SCHEMBL28187947 0.91 PNMT (0.59) PNMTPDE2ALMNACES2MEN1
SCHEMBL14402720 0.86 PNMT (0.66) PNMTCES2GRIN2BACP3
SCHEMBL12064796 0.86 PNMT (0.66) PNMTCES2GRIN2BACP3
SCHEMBL13850046 0.86 PNMT (0.66) PNMTCES2GRIN2BACP3
SCHEMBL14402570 0.85 PNMT (0.64) PNMTCES2GRIN2BACP3
SCHEMBL20342674 0.85 PNMT (0.64) PNMTCES2GRIN2BACP3
SCHEMBL28853269 0.84 PNMT (0.51) PNMTPDE2ACES2ACP3IDO1
SCHEMBL6055132 0.84 LMNA (0.53) PNMTLMNACYP1A2CYP3A4CYP2C9
SCHEMBL16412856 0.84 PNMT (0.72) PNMTCES2GRIN2BACP3IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023232002-A1 METHOD FOR PREPARING CARBOXYLATE BY MEANS OF IRON-CATALYZED OXIDATION AND ESTERIFICATION OF ALCOHOL 复旦大学 2023-12-07 WO disclosed