Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP7 | P09237 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.49 |
| ▸ | GPR183 | P32249 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360911 | 0.82 | LMNA (0.59) | LMNACYP2C19MMP1MMP7MMP8 | |
| SCHEMBL5352124 | 0.82 | LMNA (0.60) | LMNACYP2C19MMP1MMP7MMP8 | |
| SCHEMBL27598290 | 0.78 | LMNA (0.67) | LMNAMMP1MMP7MMP8MMP12 | |
| SCHEMBL1982673 | 0.76 | LMNA (0.50) | LMNACYP2C19MMP1MMP7MMP8 | |
| SCHEMBL5733917 | 0.76 | LMNA (0.59) | LMNAMMP1MMP7MMP8MMP12 | |
| SCHEMBL1979216 | 0.75 | LMNA (0.48) | LMNACYP2C19MMP1MMP7MMP8 | |
| SCHEMBL5348543 | 0.74 | GRIN2B (0.62) | LMNAFAAHHDAC6 | |
| SCHEMBL6222918 | 0.72 | LMNA (0.48) | LMNA | |
| SCHEMBL1983279 | 0.72 | LMNA (0.45) | LMNAMMP1MMP7MMP8MMP12 | |
| SCHEMBL2015601 | 0.71 | GAA (0.61) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447385-A | Preparation and application of deuterated 3-aminomethyl-4-phenylpiperidin-4-ol compound | 南昌双天使生物科技开发有限公司 | 2024-01-26 | — | — | CN | disclosed |