Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.64 |
| ▸ | HTR1A | P08908 | 4/20 | 0.63 |
| ▸ | HTR2A | P28223 | 4/20 | 0.63 |
| ▸ | HTR7 | P34969 | 1/20 | 0.63 |
| ▸ | HTR6 | P50406 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23409245 | 1.00 | DRD2 (0.64) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL30728641 | 0.97 | DRD2 (0.67) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL23409238 | 0.97 | DRD2 (0.67) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL20489615 | 0.87 | HTR1A (0.53) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL23409230 | 0.87 | DRD2 (0.59) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL30728646 | 0.87 | DRD2 (0.59) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL18823620 | 0.86 | HTR1A (0.55) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL23409258 | 0.85 | DRD2 (0.55) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL23409256 | 0.85 | DRD2 (0.55) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL30728637 | 0.85 | DRD2 (0.55) | DRD2HTR1AHTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728956-B | Fused heterocyclic derivative and application thereof | 上海枢境生物科技有限公司 | 2024-01-12 | — | — | CN | disclosed |