Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2077862 | 0.92 | ALDH1A1 (0.47) | GAAALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL24130978 | 0.92 | ALDH1A1 (0.43) | GAAALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL30002131 | 0.92 | ALDH1A1 (0.47) | GAAALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL2643585 | 0.90 | ALDH1A1 (0.50) | GAAALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL10848836 | 0.90 | ALDH1A1 (0.50) | GAAALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL2184889 | 0.87 | HRH1 (0.46) | GAAALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL32665351 | 0.87 | HRH1 (0.46) | GAAALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL4863817 | 0.87 | GAA (0.40) | GAAALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL30137583 | 0.87 | GAA (0.40) | GAAALDH1A1MAPTKMT2AHPGD | |
| Hydrochloric Acid SCHEMBL1677150 | 0.86 | HRH1 (0.45) | GAAALDH1A1MAPTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4538269-A1 | SUBSTITUTED PYRIDAZINE-3-CARBOXAMIDE COMPOUND SERVING AS TYK2 INHIBITOR | Guangzhou Fermion Technology Co., Ltd. (CN) | 2025-04-16 | — | — | EP | disclosed |
| EP-4538268-A1 | PYRIDAZIN-3-CARBOXAMIDE COMPOUND AS TYK2 INHIBITOR | Guangzhou Fermion Technology Co., Ltd. (CN) | 2025-04-16 | — | — | EP | disclosed |
| CN-117186075-A | Substituted pyridazine-3-carboxamide compounds as TYK2 inhibitors | 广州费米子科技有限责任公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-117186074-A | Pyridazine-3-carboxamide compounds as TYK2 inhibitors | 广州费米子科技有限责任公司 | 2023-12-08 | — | — | CN | disclosed |