Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PKLR | P30613 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30729277 | 0.84 | SLC22A12 (0.41) | P2RX3P2RX2PKMPKLRRAB9A | |
| SCHEMBL29279390 | 0.84 | RECQL (0.47) | RECQLP2RX3P2RX2MPOHSD17B10 | |
| SCHEMBL29279367 | 0.77 | RECQL (0.44) | RECQLP2RX3P2RX2MPOHSD17B10 | |
| SCHEMBL29279380 | 0.73 | SMN1; SMN2 (0.44) | RECQLP2RX3P2RX2HSD17B10TSHR | |
| SCHEMBL29279366 | 0.73 | ALDH1A1 (0.45) | RECQLP2RX3P2RX2HSD17B10BRD4 | |
| SCHEMBL18164294 | 0.71 | RECQL (0.43) | RECQLMPOHSD17B10IDO1PKM | |
| SCHEMBL2543455 | 0.68 | RECQL (0.66) | RECQLHSD17B10TSHRBRD4ALDH1A1 | |
| SCHEMBL30694932 | 0.68 | RECQL (0.66) | RECQLHSD17B10TSHRBRD4ALDH1A1 | |
| SCHEMBL1169734 | 0.68 | RECQL (0.60) | RECQLMPOHSD17B10TSHRBRD4 | |
| SCHEMBL15687378 | 0.67 | RECQL (0.55) | RECQLMPOHSD17B10TSHRBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114014842-B | Heterocyclic ketone compound and composition thereof, and preparation method and application thereof | 中国药科大学 | 2024-03-01 | — | — | CN | disclosed |