Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 12/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.31 |
| ▸ | PKLR | P30613 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30729352 | 0.84 | RECQL (0.42) | MAPTPKMP2RX3P2RX2PKLR | |
| SCHEMBL29279375 | 0.78 | SLC22A12 (0.43) | SLC22A12NPBWR1PKMNPC1RAB9A | |
| SCHEMBL30729333 | 0.74 | SLC22A12 (0.45) | SLC22A12NPBWR1MAPTPKMNPC1 | |
| SCHEMBL29279372 | 0.74 | SLC22A12 (0.45) | SLC22A12NPBWR1MAPTPKMNPC1 | |
| SCHEMBL30729331 | 0.71 | KMO (0.50) | SLC22A12NPBWR1 | |
| SCHEMBL29279354 | 0.71 | KMO (0.50) | SLC22A12NPBWR1 | |
| SCHEMBL30207655 | 0.70 | SLC22A12 (0.42) | SLC22A12NPBWR1 | |
| SCHEMBL24211043 | 0.69 | NPBWR1 (0.38) | SLC22A12NPBWR1MAPTNPC1RAB9A | |
| SCHEMBL16587409 | 0.69 | SLC22A12 (0.64) | SLC22A12 | |
| SCHEMBL11977253 | 0.68 | SLC22A12 (0.65) | SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114014842-B | Heterocyclic ketone compound and composition thereof, and preparation method and application thereof | 中国药科大学 | 2024-03-01 | — | — | CN | disclosed |