Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | STK17B | O94768 | 1/20 | 0.32 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.32 |
| ▸ | BUB1 | O43683 | 1/20 | 0.32 |
| ▸ | F13A1 | P00488 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | TGM1 | P22735 | 1/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27075940 | 1.00 | POLB (0.36) | POLBNR1H2NR1H3HDAC1HDAC6 | |
| SCHEMBL29986081 | 0.81 | POLB (0.38) | POLBNR1H2NR1H3HDAC1HDAC6 | |
| SCHEMBL23089780 | 0.81 | POLB (0.38) | POLBNR1H2NR1H3HDAC1HDAC6 | |
| SCHEMBL27075952 | 0.81 | POLB (0.38) | POLBNR1H2NR1H3HDAC1HDAC6 | |
| SCHEMBL29736458 | 0.80 | HDAC1 (0.36) | POLBNR1H2HDAC1HDAC6BUB1 | |
| SCHEMBL23089773 | 0.80 | HDAC1 (0.36) | POLBNR1H2HDAC1HDAC6BUB1 | |
| SCHEMBL23090067 | 0.78 | UCHL1 (0.36) | POLBHDAC1HDAC6BUB1F13A1 | |
| SCHEMBL23114725 | 0.76 | POLB (0.38) | POLBNR1H2NR1H3HDAC1HDAC6 | |
| SCHEMBL31303368 | 0.75 | BUB1 (0.36) | POLBNR1H2NR1H3HDAC1HDAC6 | |
| SCHEMBL23090018 | 0.75 | BUB1 (0.36) | POLBNR1H2NR1H3HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117377673-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2024-01-09 | — | — | CN | disclosed |