Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.48 |
| ▸ | KDR | P35968 | 14/20 | 0.47 |
| ▸ | BRAF | P15056 | 10/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27305737 | 0.84 | KDR (0.54) | MAPK14KDRBRAF | |
| SCHEMBL27096971 | 0.83 | MAPK14 (0.52) | MAPK14KDRBRAF | |
| SCHEMBL30729926 | 0.81 | MAPK14 (0.46) | MAPK14KDRBRAF | |
| SCHEMBL29834742 | 0.76 | KDR (0.51) | MAPK14KDRBRAF | |
| SCHEMBL27299410 | 0.75 | KDM4E (0.50) | MAPK14KDRBRAFNOS1NOS2 | |
| SCHEMBL30729921 | 0.74 | MAPK14 (0.40) | MAPK14KDRBRAF | |
| SCHEMBL30729895 | 0.74 | KDR (0.40) | MAPK14KDRBRAF | |
| SCHEMBL27311398 | 0.73 | KDR (0.66) | KDRBRAF | |
| SCHEMBL27097019 | 0.72 | KDM4E (0.44) | MAPK14KDRBRAFNOS1NOS2 | |
| SCHEMBL27096992 | 0.72 | KDR (0.64) | KDRBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026056-A2 | HETEROARYL COMPOUNDS AS EGFR INHIBITORS AND THEIR USES | ACCUTAR BIOTECHNOLOGY, INC. (US) | 2024-02-01 | — | — | WO | disclosed |