Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 5/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 5/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27096999 | 1.00 | POLB (0.51) | POLBMAPK1SCN1ASCN5ASCN8A | |
| SCHEMBL27096871 | 0.79 | MAPT (0.45) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL31379518 | 0.73 | POLB (0.42) | POLBMAPK1SCN1ASCN5ASCN8A | |
| SCHEMBL2103199 | 0.72 | CSNK2A1 (0.61) | POLBCSNK2A1ALDH1A1GAACYP3A4 | |
| SCHEMBL12173109 | 0.71 | RORC (0.58) | POLBMAPK1SCN1ASCN5ASCN8A | |
| SCHEMBL2194043 | 0.70 | SYK (0.46) | POLBNPC1RAB9ACYP3A4KMT2A | |
| SCHEMBL8309503 | 0.70 | POLB (0.45) | POLBMAPK1CSNK2A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2195908 | 0.69 | SYK (0.45) | POLBCSNK2A1NPC1RAB9AALDH1A1 | |
| SCHEMBL2033241 | 0.68 | POLB (1.00) | POLBMAPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8308295 | 0.67 | POLB (0.44) | POLBMAPK1SCN1ASCN5ASCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026056-A2 | HETEROARYL COMPOUNDS AS EGFR INHIBITORS AND THEIR USES | ACCUTAR BIOTECHNOLOGY, INC. (US) | 2024-02-01 | — | — | WO | disclosed |