Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.36 |
| ▸ | NR2C2 | P49116 | 3/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.36 |
| ▸ | RELA | Q04206 | 3/20 | 0.36 |
| ▸ | TAB1 | Q15750 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 3/20 | 0.34 |
| ▸ | AXL | P30530 | 2/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27096964 | 0.82 | OPRD1 (0.35) | CCR6LRRK2 | |
| SCHEMBL27299392 | 0.81 | LRRK2 (0.35) | ALDH1A1TSHRCCR6LRRK2 | |
| SCHEMBL27096813 | 0.77 | MAPK14 (0.41) | MAPK13METKDR | |
| SCHEMBL27309934 | 0.74 | KDR (0.41) | MAPK13METKDR | |
| SCHEMBL29834832 | 0.72 | MAP4K4 (0.39) | MAPK13MAPTALDH1A1GAATSHR | |
| SCHEMBL27096991 | 0.71 | LRRK2 (0.39) | TGFBR1KDRLRRK2 | |
| SCHEMBL16775755 | 0.70 | EIF2AK4 (0.37) | MAPTGAACCR6LRRK2 | |
| SCHEMBL11959104 | 0.67 | HRH4 (0.47) | MAPK13NFKB1NR2C2NFKB2RELA | |
| SCHEMBL27096935 | 0.66 | KDR (0.45) | MAPK13METKDR | |
| SCHEMBL13232321 | 0.66 | HRH4 (0.49) | MAPK13NFKB1NR2C2NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026056-A2 | HETEROARYL COMPOUNDS AS EGFR INHIBITORS AND THEIR USES | ACCUTAR BIOTECHNOLOGY, INC. (US) | 2024-02-01 | — | — | WO | disclosed |