SCHEMBL30729964

SCHEMBL30729964

COc1cc(-c2ccc(-c3ccc(C=O)cc3)cc2)c(OC)cc1C=O

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.55
TSHR P16473 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
KDM4E B2RXH2 1/20 0.55
ERN1 O75460 8/20 0.44
HPGD P15428 2/20 0.44
AOX1 Q06278 1/20 0.44
TRIM24 O15164 1/20 0.44
ALDH5A1 P51649 1/20 0.44
ABAT P80404 1/20 0.44
TRIM33 Q9UPN9 1/20 0.44
CYP2A6 P11509 1/20 0.43
PRKDC P78527 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MAPT P10636 1/20 0.42
LMNA P02545 1/20 0.41
FDPS P14324 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30865006 0.93 ALDH1A1 (0.62) ALDH1A1TSHRTDP1KDM4EERN1
SCHEMBL24663368 0.90 ALDH1A1 (0.57) ALDH1A1TSHRTDP1HPGDAOX1
SCHEMBL9717769 0.83 ALDH1A1 (0.58) ALDH1A1TSHRTDP1KDM4EERN1
SCHEMBL30865007 0.80 ALDH1A1 (0.75) ALDH1A1TSHRTDP1KDM4EERN1
SCHEMBL6224414 0.77 ALDH1A1 (0.58) ALDH1A1TSHRTDP1KDM4EERN1
SCHEMBL3136850 0.76 ALDH1A1 (0.90) ALDH1A1TSHRTDP1KDM4EERN1
SCHEMBL26628327 0.75 ALDH1A1 (0.58) ALDH1A1TSHRTDP1KDM4EERN1
SCHEMBL12740233 0.75 ERN1 (0.58) ALDH1A1TSHRTDP1ERN1HPGD
SCHEMBL2002821 0.74 ERN1 (0.59) ALDH1A1TSHRTDP1ERN1HPGD
SCHEMBL12459049 0.74 ALDH1A1 (0.51) ALDH1A1TSHRTDP1KDM4EERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117624520-A Trifluoromethyl modified pyrenyl covalent organic framework material, and preparation method and application thereof 中国石油大学(华东) 2024-03-01 CN claimed
CN-117624520-A Trifluoromethyl modified pyrenyl covalent organic framework material, and preparation method and application thereof 中国石油大学(华东) 2024-03-01 CN disclosed