SCHEMBL9717769

SCHEMBL9717769

COc1cc(-c2ccccc2)c(OC)cc1C=O

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.58
KDM4E B2RXH2 2/20 0.58
TSHR P16473 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
ERN1 O75460 8/20 0.48
PGR P06401 1/20 0.48
FGFR1 P11362 1/20 0.46
MAPT P10636 3/20 0.44
PRKDC P78527 1/20 0.44
LMNA P02545 1/20 0.44
HPGD P15428 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
NPC1 O15118 1/20 0.43
POLB P06746 1/20 0.43
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6224414 0.93 ALDH1A1 (0.58) ALDH1A1KDM4ETSHRTDP1ERN1
SCHEMBL30865006 0.89 ALDH1A1 (0.62) ALDH1A1KDM4ETSHRTDP1ERN1
SCHEMBL12121709 0.89 ALDH1A1 (0.49) ALDH1A1KDM4ETSHRTDP1ERN1
SCHEMBL30729964 0.83 ALDH1A1 (0.55) ALDH1A1KDM4ETSHRTDP1ERN1
SCHEMBL30865007 0.83 ALDH1A1 (0.75) ALDH1A1KDM4ETSHRTDP1ERN1
SCHEMBL24049723 0.83 PGR (0.56) ALDH1A1KDM4EPGRMAPTLMNA
SCHEMBL14027797 0.81 PGR (0.54) ALDH1A1KDM4EPGRMAPTMEN1
SCHEMBL17229426 0.80 ALDH1A1 (0.53) ALDH1A1KDM4ETSHRTDP1ERN1
SCHEMBL28988462 0.80 ALDH1A1 (0.46) ALDH1A1KDM4ETSHRTDP1ERN1
SCHEMBL24310954 0.79 PDCD1 (0.57) ALDH1A1KDM4ETSHRTDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0211898-B1 REDUCIBLE COMPOUNDS AND ANALYTICAL COMPOSITIONS, ELEMENTS AND ME THODS UTILIZING SAME EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-04-15 EP disclosed
US-5045477-A Medical diagnosis EASTMAN KODAK COMPANY (US) 1991-09-03 US disclosed
US-4857271-A USING A QUINONE COMPOUND EASTMAN KODAK COMPANY (US) 1989-08-15 US disclosed
US-4803161-A DYE RELEASE ON REDUCTION BY MICROORGANISMS EASTMAN KODAK COMPANY (US) 1989-02-07 US disclosed
EP-0232130-A2 Biological and analytical uses of phenalenone and benzphenalenone compounds EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-08-12 EP disclosed
EP-0211898-A1 REDUCIBLE COMPOUNDS AND ANALYTICAL COMPOSITIONS, ELEMENTS AND ME THODS UTILIZING SAME. EASTMAN KODAK CO (US) 1987-03-04 EP disclosed
WO-1986004681-A1 REDUCIBLE COMPOUNDS AND ANALYTICAL COMPOSITIONS, ELEMENTS AND ME THODS UTILIZING SAME EASTMAN KODAK COMPANY (US) 1986-08-14 WO disclosed