Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.45 |
| ▸ | DRD2 | P14416 | 9/20 | 0.45 |
| ▸ | DRD4 | P21917 | 9/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27362243 | 0.80 | HTR1A (0.41) | HTR1ADRD2DRD4KCNH2IRAK4 | |
| SCHEMBL30730035 | 0.79 | HTR1A (0.46) | HTR1ADRD2DRD4KCNH2IRAK4 | |
| SCHEMBL23006094 | 0.77 | HTR1A (0.44) | HTR1ADRD2DRD4KCNH2IRAK4 | |
| SCHEMBL30730324 | 0.77 | CNR2 (0.42) | HTR1ADRD2DRD4KCNH2CNR2 | |
| SCHEMBL2545447 | 0.74 | ALDH1A1 (0.42) | ALDH1A1GAAKMT2ATSHR | |
| SCHEMBL2545445 | 0.74 | ALDH1A1 (0.42) | ALDH1A1GAAKMT2ATSHR | |
| SCHEMBL17730071 | 0.73 | HTR1A (0.43) | HTR1ADRD2DRD4KCNH2IRAK4 | |
| SCHEMBL30404315 | 0.73 | CYP1A2 (0.45) | ALDH1A1GAAHPGDKMT2ATSHR | |
| SCHEMBL31096150 | 0.72 | CYP1A2 (0.44) | IRAK4ALDH1A1GAAHPGDKMT2A | |
| SCHEMBL2183402 | 0.72 | CYP1A2 (0.44) | ALDH1A1GAAHPGDKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4562015-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | Cedilla Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026481-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |