Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30443832 | 0.84 | TSHR (0.44) | HDAC3HDAC1HDAC2HDAC6SSTR4 | |
| SCHEMBL10228105 | 0.83 | KMO (0.42) | HDAC6GAACYP2C19ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL604111 | 0.82 | KMO (0.41) | HDAC6GAACYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL8443184 | 0.80 | KMT2A (0.52) | HDAC3HDAC1HDAC2HDAC6SSTR4 | |
| SCHEMBL3323151 | 0.80 | FFAR2 (0.52) | CYP2C19ALDH1A1POLBFFAR2MEN1 | |
| SCHEMBL30730227 | 0.79 | GAA (0.44) | HDAC3HDAC1HDAC2HDAC6GAA | |
| SCHEMBL27329721 | 0.79 | GAA (0.44) | HDAC3HDAC1HDAC2HDAC6GAA | |
| SCHEMBL10228094 | 0.79 | NPC1 (0.38) | HDAC1HDAC6ALDH1A1POLBKMT2A | |
| SCHEMBL1626481 | 0.78 | AKR1C3 (0.51) | HDAC3HDAC1HDAC2HDAC6SSTR4 | |
| SCHEMBL1627092 | 0.78 | TSHR (0.48) | HDAC3HDAC1HDAC2HDAC6SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4562015-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | Cedilla Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026481-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |