Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30066427 | 0.83 | KMT2A (0.50) | NPC1RAB9AKMT2AMEN1ELANE | |
| SCHEMBL4553548 | 0.83 | KMT2A (0.50) | NPC1RAB9AKMT2AMEN1ELANE | |
| SCHEMBL18542560 | 0.78 | HDAC8 (0.58) | HDAC8 | |
| Oxalic Acid SCHEMBL14810479 | 0.76 | KMO (0.46) | NPC1RAB9AKMT2AMEN1ELANE | |
| SCHEMBL8725006 | 0.76 | KMO (0.43) | NPC1RAB9AKMT2AMEN1ELANE | |
| SCHEMBL14722845 | 0.76 | RECQL (0.39) | NPC1RAB9AKMT2AMEN1ELANE | |
| SCHEMBL17269342 | 0.75 | NPC1 (0.51) | NPC1RAB9AKMT2AMEN1KMO | |
| SCHEMBL29350890 | 0.75 | RECQL (0.43) | NPC1RAB9AKMT2AMEN1ELANE | |
| SCHEMBL878425 | 0.75 | RECQL (0.43) | NPC1RAB9AKMT2AMEN1ELANE | |
| SCHEMBL6281573 | 0.72 | ELANE (0.40) | NPC1RAB9AKMT2AMEN1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4562015-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | Cedilla Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026481-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |