Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30087732 | 0.80 | CA1 (0.52) | CA1CA2ALDH1A1MAPTLMNA | |
| SCHEMBL20325773 | 0.79 | MAPT (0.49) | CA1CA2PDK1PDK2PDK3 | |
| SCHEMBL17420611 | 0.78 | CA1 (0.50) | CA1CA2ALDH1A1MAPTLMNA | |
| SCHEMBL5740555 | 0.78 | KCNN4 (0.48) | ALDH1A1MAPTHTTMAPK1KDM4E | |
| SCHEMBL30730384 | 0.77 | ALDH1A1 (0.52) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL28637684 | 0.77 | MAPT (0.46) | CA1CA2PDK1PDK2PDK3 | |
| SCHEMBL21501142 | 0.77 | CA1 (0.48) | CA1CA2ALDH1A1MAPTLMNA | |
| SCHEMBL16147948 | 0.75 | CES2 (0.53) | CA1CA2ALDH1A1MAPTLMNA | |
| SCHEMBL18262545 | 0.74 | CA1 (0.50) | CA1CA2PDK1PDK2PDK3 | |
| SCHEMBL18262542 | 0.74 | CA1 (0.50) | CA1CA2PDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4562015-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | Cedilla Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026481-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |