Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.42 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.41 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.41 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.39 |
| ▸ | CD38 | P28907 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22553975 | 1.00 | TBK1 (0.44) | TBK1NUDT1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL30731110 | 0.92 | NUDT1 (0.46) | TBK1NUDT1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL30730826 | 0.90 | NUDT1 (0.43) | TBK1NUDT1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL22553745 | 0.90 | TBK1 (0.45) | TBK1NUDT1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL30731117 | 0.90 | NUDT1 (0.43) | TBK1NUDT1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL22554135 | 0.90 | NUDT1 (0.57) | TBK1NUDT1ALDH1A1NPC1CYP11B2 | |
| SCHEMBL22553938 | 0.90 | NUDT1 (0.43) | TBK1NUDT1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL22554164 | 0.89 | NUDT1 (0.48) | TBK1NUDT1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL22553987 | 0.89 | NPC1 (0.48) | TBK1NUDT1ALDH1A1NPC1DGAT2 | |
| SCHEMBL30730854 | 0.89 | NPC1 (0.48) | TBK1NUDT1ALDH1A1NPC1DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | claimed |
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | disclosed |