Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | TTK | P33981 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11575773 | 0.82 | KDM4E (0.54) | DYRK1AHRH3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL30577111 | 0.81 | CYP2A6 (0.60) | GSK3BALDH1A1CYP2A6CYP2A13HSD17B10 | |
| SCHEMBL27856754 | 0.78 | GRM2 (0.53) | JAK2NPC1RAB9ACOMTGRM2 | |
| SCHEMBL26240869 | 0.78 | CHEK1 (0.46) | HRH3ALDH1A1KDM4ESMN1; SMN2TP53 | |
| SCHEMBL29348780 | 0.78 | HRH3 (0.43) | HRH3ALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL12987761 | 0.78 | HRH3 (0.43) | HRH3ALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL23512903 | 0.75 | HRH3 (0.44) | HRH3ALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL27250757 | 0.75 | ALDH1A1 (0.40) | HRH3GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL12263289 | 0.74 | HPGD (0.46) | JAK2HRH3ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL21595065 | 0.74 | HRH3 (0.43) | HRH3ALDH1A1KDM4ESMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642399-A | Pyrrolopyridone derivatives useful for the treatment of cancer | 泰治疗有限公司 | 2024-03-01 | — | — | CN | disclosed |