Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.35 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30310881 | 0.81 | KDM4E (0.41) | KDM4ERAD52ALKFGFR3EML4 | |
| SCHEMBL27038486 | 0.80 | KDM4E (0.40) | KDM4ERAD52ACVR1ALKFGFR3 | |
| SCHEMBL24773694 | 0.77 | SMN1; SMN2 (0.60) | GAAALOX12SMN1; SMN2SLC18A3KDM4E | |
| SCHEMBL23932948 | 0.76 | FGFR3 (0.40) | KDM4EACVR1ALKFGFR3EML4 | |
| SCHEMBL27038765 | 0.76 | FGFR3 (0.40) | KDM4EACVR1ALKFGFR3EML4 | |
| SCHEMBL27038695 | 0.76 | FGFR3 (0.36) | GAAALOX12SMN1; SMN2KDM4EACVR1 | |
| SCHEMBL1461677 | 0.75 | NCF1 (0.45) | L3MBTL1KDM4ERAD52ACHEMEN1 | |
| SCHEMBL27038484 | 0.75 | FLT3 (0.41) | KDM4EACVR1ALKFGFR3EML4 | |
| SCHEMBL15759136 | 0.74 | MAPT (0.48) | GAAALOX12SMN1; SMN2SLC18A3ALK | |
| SCHEMBL22942872 | 0.73 | FGFR3 (0.41) | KDM4EALKFGFR3EML4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024017258-A1 | EGFR SMALL MOLECULE INHIBITOR, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | 百极弘烨(南通)医药科技有限公司 | 2024-01-25 | — | — | WO | disclosed |