Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722525 | 0.85 | NCF1 (0.58) | NCF1LMNAHTR1ADRD2DRD4 | |
| SCHEMBL1460326 | 0.84 | ACHE (0.43) | ACHELMNAOPRL1KDM4EL3MBTL1 | |
| SCHEMBL5073795 | 0.77 | MEN1 (0.42) | NCF1KDM4EALDH1A1HTR1ADRD2 | |
| SCHEMBL1461471 | 0.76 | NPY1R (0.40) | NCF1MEN1KMT2A | |
| SCHEMBL26407202 | 0.76 | ADRA2C (0.70) | NCF1RECQLKDM4EPOLBL3MBTL1 | |
| SCHEMBL30730965 | 0.75 | GAA (0.44) | ACHERECQLKDM4EPOLBL3MBTL1 | |
| SCHEMBL1460335 | 0.74 | SMN1; SMN2 (0.37) | NCF1RECQLOPRL1KDM4EPOLB | |
| SCHEMBL30310881 | 0.74 | KDM4E (0.41) | KDM4EALDH1A1RAD52MAPT | |
| SCHEMBL1461519 | 0.74 | CBX7 (0.40) | KDM4EALDH1A1DRD3MAPTMEN1 | |
| SCHEMBL27038486 | 0.73 | KDM4E (0.40) | KDM4EALDH1A1RAD52DRD3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011026959-A1 | NOVEL ETHANE DIAMINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2011-03-10 | — | — | WO | disclosed |